Gastroenterology, Digestive Diseases, Hepatology & Nutrition


Did You Know?

Dr. Sylvester was born in Peru. He plays acoustic guitar and is a fan of the New York Mets.

Francisco Sylvester, MD


Education: MD, Universidad Peruana Cayetano Heredia, 1977-1985
Residency: Pediatrics, SUNY-Brooklyn, 1987-1990 (Chief Resident 1990-1991)
Fellowship: Pediatric Gastroenterology, Hospital for Sick Children, 1991-1995

Board Certifications

Pediatric Gastroenterology

Faculty Appointment

Professor of Pediatrics and Immunology, University of Connecticut School of Medicine


Dr. Sylvester maintains an active collaboration with Dr. Anthony T. Vella within the department of immunology at the University of Connecticut Health Center to study immune responses in children with inflammatory bowel diseases. He is an expert in the impact of chronic digestive diseases in bone health in children. Dr. Sylvester is an active volunteer for the Crohn's and Colitis Foundation of America and currently serves as a member of their Board of Trustees.

Published Research

  • Rufo PA, Denson LA, Sylvester FA, Szigethy E, Sathya P, Lu Y, Wahbeh GT, Sena LM, Faubion WA. Health supervision in the management of children and adolescents with IBD: NASPGHAN recommendations. J Pediatr Gastroenterol Nutr. 2012 Jul;55(1):93-108. PubMed PMID: 22516861.
  • Ngoi SM, Sylvester FA, Vella AT. The role of microbial byproducts in protection against immunological disorders and the hygiene hypothesis. Discov Med. 2011 Nov;12(66):405-12. PubMed PMID: 22127111.
  • Sylvester FA, Turner D, Draghi A 2nd, Uuosoe K, McLernon R, Koproske K, Mack DR, Crandall WV, Hyams JS, Leleiko NS, Griffiths AM. Fecal osteoprotegerin may guide the introduction of second-line therapy in hospitalized children with ulcerative colitis. Inflamm Bowel Dis. 2011 Aug;17(8):1726-30.doi: 10.1002/ibd.21561. Epub 2010 Dec 3. PubMed PMID: 21744427.
  • Bennett WE Jr, González-Rivera R, Puente BN, Shaikh N, Stevens HJ, Mooney JC, Klein EJ, Denno DM, Draghi A II, Sylvester FA, Tarr PI. Proinflammatory fecal mRNA and childhood bacterial enteric infections. Gut Microbes. 2010 Jul;1(4):209-212. Epub 2010 Jul 13. PubMed PMID: 21327027; PubMed Central PMCID: PMC3023602.
  • Goh VL, Estrada DE, Lerer T, Balarezo F, Sylvester FA. Effect of gluten-free diet on growth and glycemic control in children with type 1 diabetes and asymptomatic celiac disease. J Pediatr Endocrinol Metab. 2010 Nov;23(11):1169-73. PubMed PMID: 21284331.
  • Sylvester FA. The impact of gastrointestinal and liver diseases on bone: it ain't like menopause! Gastroenterology. 2011 Jan;140(1):22-5. Epub 2010 Nov 24. PubMed PMID: 21110963.
  • Sylvester FA, Leopold S, Lincoln M, Hyams JS, Griffiths AM, Lerer T. A two-year longitudinal study of persistent lean tissue deficits in children with Crohn's disease. Clin Gastroenterol Hepatol. 2009 Apr;7(4):452-5. Epub 2008 Dec 27. PubMed PMID: 19249399.
  • Francolla KA, Altman A, Sylvester FA. Hemophagocytic syndrome in an adolescent with Crohn disease receiving azathioprine and infliximab. J Pediatr Gastroenterol Nutr. 2008 Aug;47(2):193-5. PubMed PMID: 18664872.
  • Viswanathan A, Sylvester FA. Chronic pediatric inflammatory diseases: effects on bone. Rev Endocr Metab Disord. 2008 Jun;9(2):107-22. Epub 2007 Dec 29. Review. PubMed PMID: 18165904.
  • Sylvester FA, Wyzga N, Hyams JS, Davis PM, Lerer T, Vance K, Hawker G, Griffiths AM. Natural history of bone metabolism and bone mineral density in children with inflammatory bowel disease. Inflamm Bowel Dis. 2007 Jan;13(1):42-50. PubMed PMID: 17206638.
  • Pappa H, Thayu M, Sylvester F, Leonard M, Zemel B, Gordon C. Skeletal health of children and adolescents with inflammatory bowel disease. J Pediatr Gastroenterol Nutr. 2011 Jul;53(1):11-25. Erratum in: J Pediatr Gastroenterol Nutr. 2012 Apr;54(4):571. PubMed PMID: 21694532; PubMed Central PMCID: PMC3122140.