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MSc, University of Connecticut, 2012
MD, Tufts University School of Medicine, 1998
BS, University of Connecticut, 1993
Pediatrics, Baystate Medical Center, 1998-2001
Neonatology, University of Connecticut Health and Connecticut Children’s, 2001-2004
Assistant Professor of Pediatrics and Immunology, University of Connecticut School of Medicine
Adam Matson, MD, MSc, is a Neonatologist and Physician Scientist in the Division of Neonatology at Connecticut Children’s. Dr. Matson’s clinical expertise is in neonatal intensive care. He also runs a basic/translational research laboratory at the University of Connecticut School of Medicine and is Director of Connecticut Children’s Neonatal Biorepository. He has served as principal investigator and collaborator/physician-scientist on grants from the American Lung Association, National Institute of Allergy and Infectious Diseases, and National Heart Lung and Blood Institute.
His current research focus is on the regulation of intestinal health in premature infants including the microbiome, inflammatory signaling in the gut, and nutritional/immune factors in breast milk. His group was the first to report a link between cytotoxin-producing Klebsiella oxytoca and necrotizing enterocolitis, a severe and life-threatening intestinal inflammatory disease of premature infants. Dr. Matson serves as a member of the Neonatal Fellowship Scholarly Oversight Committee and has mentored several fellows whose projects have led to high impact publications and presentations at national and international meetings. In his free time, Dr. Matson enjoys the outdoors and spending time with his family.
Ledala N, Malik M, Rezaul K, Paveglio S, Provatas A, Kiel A, Caimano M, Zhou Y, Lindgren J, Krasulova K, Illes P, Dvořák Z, Kortagere S, Kienesberger S, Cosic A, Pöltl L, Zechner EL, Ghosh S, Mani S, Radolf JD, Matson AP. Bacterial Indole as a Multifunctional Regulator of Klebsiella oxytoca Complex Enterotoxicity. mBio. 2022 Jan 25; [Epub ahead of print]. PMCID: PMC8787480.
Graf J, Ledala N, Caimano MJ, Jackson E, Gratalo D, Fasulo D, Driscoll MD, Coleman S, Matson AP. Tracking Closely Related Enteric Bacteria at High Resolution in Fecal Samples of Premature Infants Using a Novel rRNA Amplicon. mBio. 2021 Feb 16:12(1):e03656-20. PMCID: PMC8545133.
Paveglio S, Ledala N, Rezaul K, Lin Q, Zhou Y, Provatas AA, Bennett E, Lindberg T, Caimano M, Matson AP. Cytotoxin-producing Klebsiella oxytoca in the preterm gut and its association with necrotizing enterocolitis. Emerg Microbes Infect. 2020 Dec;9(1):1321-1329. PMCID: PMC7473113.
Lindberg TP, Caimano MJ, Hagadorn JI, Bennett EM, Maas K, Brownell EA, Matson AP. Preterm infant gut microbial patterns related to the development of necrotizing enterocolitis. J Matern Fetal Neonatal Med. 2020 Feb;33(3):349-358. PMID:29909714.
Huang K, Mukherjee S, DesMarais, V, Albanese JM, Rafti E, Draghi A, Maher LA, Khanna KM, Mani S, Matson AP. Targeting the PXR-TLR4 signaling pathway to reduce intestinal inflammation in an experimental model of necrotizing enterocolitis. Pediatr Res. 2018 May;83(5):1031-1040. PMCID: PMC5959752.