Christopher Carroll, MD, MS

Education

Education:
BS, Georgetown University, 1992
MD, Georgetown University School of Medicine, 1996
MS, University of Connecticut
Residency:
Pediatrics, Children’s Memorial Hospital, 1996-1999
Fellowship:
Pediatric Critical Care, Children’s Memorial Hospital, 1999-2002

Board Certifications

Faculty Appointment

Professor of Pediatrics, University of Connecticut School of Medicine

Clinical Expertise

Dr. Carroll is an active and productive researcher, administrator, educator, and clinician at Connecticut Children’s Medical Center. The primary focus of Dr. Carroll’s research is to examine the relationship between a child’s genetics and the development of disease, particularly bronchiolitis and severe asthma. With the support of Connecticut Children’s Investigator Development Program and help from an outstanding research staff including Kate Sala, Jim Santanelli, and Dayna Kennedy, Dr. Carroll has published more than 200 peer-reviewed manuscripts, book chapters and scientific abstracts, and has received several awards for his research.

Dr. Carroll has been active in improving the quality and safety of care provided to children in the PICU, and participates in several national quality committees within the NIH and the CDC. Dr. Carroll is active in the leadership of several national and international groups, including the American College of Chest Physicians, the Society of Critical Care Medicine, the American Thoracic Society, and  the Pediatric Acute Lung Injury and Sepsis Investigators Network. He also serves as an associate editor of the journal CHEST and chair of the New Media Workgroup for CHEST. Dr. Carroll is also a strong advocate of the use of social media to educate, support and advocate, and can be reached on Twitter @ChrisCarrollMD.

Selected Publications

• Carroll CL, Bruno K, vonTschudi M. Free open access medical education and social media: the future of medical and nursing education? Am J Crit Care 2016; 25(1):93-96.

• Bhandari A, Carroll CL, Bhandari V. BPD following preterm birth: A model for chronic lung disease and a substrate for ARDS in childhood. Frontiers in Pediatrics 2016; 4:1-7

• Carroll CL, EVS Faustino, Pinto M, Sala K, Canarie M, Giuliano J, Li S. A regional cohort study of the treatment of critically ill children with bronchiolitis. J Asthma 2016

• Schramm CM, Sala K, Carroll CL. Clinical exam does not predict response to albuterol in children ventilated with bronchiolitis. Pediatr Crit Care 2016

• Carroll CL, Bruno K, Ramachandran P. Building community through a #pulmcc Twitter chat to advocate for pulmonary, critical Care, and sleep. CHEST 2017

• Hymel KP*, Herman BE, Narang SK, Graf JM, Frazier TN, Stoiko M, Christie LM, Harper NS, Carroll CL, Boos SC, Dias M, Pullin DA, Wang M, for the Pediatric Brain Injury Research Network (PediBIRN) Investigators. Potential impact of a validated screening tool for pediatric abusive head trauma. J Pediatr 2016

• Canarie MF, Barry S, Carroll CL, Hassinger A, Kandil S, Li S, Pinto M, Valentine S, EVS Faustino. Risk factors for delayed enteral nutrition in critically ill children. Pediatr Crit Care 2015; 16(8):e283-289.

• Sala KA*, Moore A, Desai S, Welch K, Bhandari S, Carroll CL. Factors associated with disease severity in children with bronchiolitis. J Asthma 2015; 52(3):268-272.

• Gupta P, Robertson MJ, Beam B, Gossett JM, Schmitz ML, Carroll CL, Edwards JD, Fortenberry JD, Butt W. Relationship of ECMO duration with outcomes after pediatric cardiac surgery: a multi-institutional analysis. Minerva Anestesiologica 2015; 81:619-627.

• Essouri S, Carroll CL, for the Pediatric Acute Lung Injury Consensus Conference Group. Noninvasive support and ventilation for pediatric acute respiratory distress syndrome: Proceedings from the pediatric acute lung injury consensus conference. Pediatr Crit Care 2015; 16(5):S102-110.

• The Pediatric Acute Lung Injury Consensus Conference Group. Pediatric Acute Respiratory Distress Syndrome: Consensus Recommendations from the Pediatric Acute Lung Injury Consensus Conference. Pediatr Crit Care 2015; 16(5):428-429.

• Choo EK, Ranney ML, Chan T, Trueger NS, Walsh AE, Tegtmeyer K, McNamara SO, Choi RY, Carroll CL. Twitter as a tool for communication and knowledge exchange in academic medicine: a guide for skeptics and novices. Medical Teacher 2015; 37(5): 411-416.

• Hymel KP*, Armijo-Garcia V, Foster R, Frazier TN, Stoiko M, Christie LM, Harper NS, Weeks K, Carroll CL, Hyden P, Sirotnak A, Truemper E, Ornstein AE, Ming Wang M. Validation of a clinical prediction rule for pediatric abusive head trauma. Pediatrics 2014; 134:e1537-1544

• Gupta P*, Tang X, Gossett JM, Gall CM, Lauer C, Rice TB, Carroll CL, Kacmarek RM, Wetzel RC. Association of center volume with outcomes in critically ill children with acute asthma: a multicenter analysis. Annals Allergy Asthma Immunol 2014; 113(1):42-47.

• Carroll CL*, Coro M, Cowl A, Sala K, Schramm CM. Transient occult cardiotoxicity in children receiving continuous beta-agonist therapy. World J Pediatr 2014; 10(4):324-9.

• Lang SM*, Giuliano JS, Carroll CL, Eisenfeld L. Neonatal/infant validations study of the CAS model 740 non-Invasive blood pressure monitor with Orion/MaxIQ NIBP module. Blood Pressure Monitoring 2014; 19(3):180-2.

• Carroll CL*, Ramachandran P. The intelligent use of digital tools and social media in practice management. Chest 2014; 145(4):896-902.

• Carroll CL*, Sala KA, Fisher D, Zucker AR. Pediatric code events: does in-house intensivist coverage improve outcomes? Pediatr Crit Care 2014; 15(3):250-257.

• Giuliano JS*, Faustino EVS, Li S, Pinto M, Canarie M, Carroll CL. Corticosteroid therapy in critically ill pediatric asthmatic patients. Pediatr Crit Care 2013; 14(5):467-470.

• Matos RI*, Watson RS, Nadkarni VM, Huang HH, Meaney PA, Carroll CL, Berg RA, Berens RJ, Praestgaard A, Weissfeld L, Spinella PC. Duration of CPR and illness category impact survival and neurologic outcomes for in-hospital pediatric cardiac arrests. Circulation 2013; 127(4):442-451.

• Carroll CL*, Just a lot of hot air?: Volatile anesthetics in children with status asthmaticus. Pediatr Crit Care 2013; 14(4):433-4.

• Carroll CL*, Sala KA. Pediatric status asthmaticus. Critical Care Clinics 2013; 29(2):153-66.

• Sala KA*, Karamessinis L, Zucker AR, Carroll CL. Respiratory failure in children with status asthmaticus: a review of the VPS database. Pediatric Allergy, Immunology, and Pulmonology 2012; 25(4): 226-230.

• Carroll CL*, Sala K, Zucker AR, Schramm CM. Pulmonary mechanics following albuterol therapy in mechanically ventilated children with bronchiolitis. J Asthma 2012; 49(7):688-696.

• Carroll CL*, Sala K, Zucker AR, Schramm CM. β2-adrenergic receptor haplotype linked to respiratory failure in children with asthma. J Asthma 2012; 49(6): 563-568.

• Carroll CL*, Sala K, Zucker AR, Schramm CM. Beta-adrenergic receptor polymorphisms and response to therapy in pediatric status asthmaticus: a prospective cohort study. Pediatr Pulmonology 2012; 47(3): 233-239.

• Sala K*, Carroll CL, Tang YD, Aglio T, Dressler A, Schramm CM. Factors associated with the development of near fatal asthma exacerbations in children. J Asthma 2011; 48(6):558-564.

• Randolph AG, Vaughn F, Sullivan R, Rubinson L, Thompson BT, Yoon G, Smoot E, Rice TW, Loftis LL, Helfaer M, Doctor A, Paden M, Flori H, Babbitt C, Graciano AL, Gedeit R, Sanders RC, Giuliano JS, Zimmerman J, Uyeki TM; Pediatric Acute Lung Injury and Sepsis Investigator’s Network and the National Heart, Lung, and Blood Institute ARDS Clinical Trials Network. Critically ill children during the 2009-2010 influenza pandemic in the United States. Pediatrics 2011; 128(6):e1450-8.

• Seifert ME, Welak SR, Carroll CL*. Hyponatremia is associated with increased severity of disease in critically ill children with bronchiolitis. Int J Clin Med 2010; 1(2):37-40.

• Spinella PC, Dressler AM*, Tucci M, Carroll CL, Rosen RS, Sloan S, Lacroix J. Survey of Transfusion Policies at US and Canadian Children’s Hospitals in 2008 and 2009. Transfusion 2010; 50(11): 2358-65.

• Santschi M*, Jouvet P, Leclerc F, Gauvin F, Newth CLJ, Carroll CL, Flori H, Tasker RC, Rimensberger PC, Randolph AR, for the PALIVE Investigators, the Pediatric Acute Lung Injury and Sepsis Investigators Network (PALISI) and the European Society of Pediatric and Neonatal Intensive Care (ESPNIC). Acute lung injury in children: therapeutic practice and feasibility of international clinical trials. Pediatr Crit Care 2010; 11(6): 681-689.

• Dressler AM*, Finck CM, Carroll CL, Bonanni CC, Spinella PC. Use of a massive transfusion protocol with hemostatic resuscitation for severe intraoperative bleeding in a child. J Pediatr Surg 2010; 45(7):1530-3.

• Carroll CL*, Uygungil B, Zucker AR, Schramm CM. Children with repeated ICU admissions for asthma: identifying an at-risk population. J Asthma 2010; 47:460-464.

• Bravo RC, Carroll CL, Schramm CM, Bhandari A*. Reassessment of disease severity in children following life-threatening asthma exacerbations. Journal of Asthma & Allergy Educators 2010; 1:56-60.

• Carroll CL*, Spinella PC, Corsi JM, Stoltz P, Zucker AR. Emergent endotracheal intubation in children: careful if it’s late when you intubate. Pediatr Crit Care 2010; 11(3):343-348.

• Carroll CL*. Heliox for children with acute asthma: has the sun set on this therapy? Pediatr Crit Care 2010; 11(3):425-426.

• Spinella PC*, Carroll CL, Staff I, Gross R, McQuay J, Wade CE, Holcomb JB. Duration of RBC storage is associated with increased incidence of deep vein thrombosis and in hospital mortality in patients with traumatic injuries. Crit Care 2009; 13(5):R151. doi:10.1186/cc8050

• Carroll CL*. Non-invasive positive pressure ventilation for the treatment of lower respiratory tract diseases in children. Clinical Pediatric Emergency Medicine 2009; 10(2):90-94.

• Schramm CM*, Carroll CL. Advances in treating acute asthma exacerbations in children. Current Opinion in Pediatrics 2009; 21(3):326-332.

• Carroll CL*, Stoltz P, Schramm CM, Zucker AR. b2-adrenergic receptor polymorphisms affect response to treatment in near fatal asthma exacerbations in children. Chest 2009; 135:1186-1192.

• Carroll CL*, Schramm CM, Zucker AR. Severe exacerbations in children with mild asthma. J Asthma 2008; 45(6):513-517.

• Carroll CL*, Schramm CM, Zucker AR. Slow responders to IV b2-adrenergic receptor agonist therapy: defining a novel phenotype in pediatric asthma. Pediatr Pulmonol 2008; 43(7):627-633.

• Carroll CL*, Zucker AR. Barotrauma not related to mode of positive pressure ventilation during severe asthma exacerbations in children. J Asthma 2008; 45(5):421-424.

• Carroll CL*, Krieger D, Campbell M, Fisher DG, Comeau LL, Zucker AR. The use of dexmedetomidine for sedation of children in the intensive care unit. J Hosp Med 2008; 3(2):142-147.

• Carroll CL*. Site of intubation and duration of mechanical ventilation in pediatric status asthmaticus. Pediatr Crit Care 2007; 8(5):509-510.

• Carroll CL*, Stoltz P, Raykov N, Smith SR, Zucker AR. Childhood overweight increases hospital admission rates for asthma. Pediatrics 2007; 120(4): 734-740.

• Carroll CL*, Zucker AR. The increased costs of complications for children with status asthmaticus. Pediatric Pulmonol 2007; 42(10):914-919.

• Carroll CL*, Smith SR, Collins M, Bhandari A, Schramm CM, Zucker AR. Endotracheal intubation and pediatric status asthmaticus: site of original care affects treatment. Pediatr Crit Care 2007; 8(2):91-95.

• Carroll CL*, Bhandari A, Zucker AR, Schramm CM. Childhood obesity increases duration of therapy during severe asthma exacerbations. Pediatr Crit Care 2006; 7(6):527-531.

• Carroll CL*, Bhandari A, Schramm CM, Zucker AR. Chronic inhaled corticosteroids do not affect acute severe asthma exacerbations in children. Pediatr Pulmonol 2006; 41:1213-1217.

• Carroll CL*, Schramm CM. Non-invasive ventilation for the treatment of status asthmaticus in children. Ann Allergy Asthma Immunol 2006; 96(3):454-459.

• Carroll CL*, Schramm CM. Protocol –based titration of intravenous terbutaline decreases length of stay in pediatric status asthmaticus. Pediatr Pulmonol 2006; 41:350-356.

• Carroll CL*, Backer CL, Mavroudis C, Cook K, Goodman DM. The use of inhaled prostacyclin following surgical repair of congenital heart disease- a pilot study. J Card Surg 2005; 20(5):436-439.

• Carroll CL*, Sekaran AK, Lerer TJ, Schramm CM. A modified pulmonary index score with predictive value for pediatric asthma exacerbations. Ann Allergy Asthma Immunol 2005; 94(3):355-359.

• Carroll CL*, Goodman DM. Endotracheal albuterol treatment of acute bronchospasm. Am J Emerg Med 2004; 22(6):506-507.

• Carroll CL*, Goodman DM, Superina RA, Whitington PF, Alonso EM. Timed pediatric risk of mortality (PRISM) scores predict outcomes in pediatric liver transplant recipients. Pediatric Transplantation 2003; 7(4):289-295.

• Kelly LM*, Porta NFM, Goodman DM, Carroll CL, Steinhorn RH. Inhaled prostacyclin for term infants with persistant pulmonary hypertension of the newborn refractory to nitric oxide. J Pediatr 2002; 141:830-2.