Health Information For Parents

What Is “PANS”?


A child at my son’s school was recently diagnosed with something called “PANS.” What is this?

PANS stands for Pediatric Acute-onset Neuropsychiatric Syndrome. Researchers are only beginning to study and understand this syndrome, so there are a lot of unanswered questions about what it is and what causes it.

What we do know is that kids with PANS have severe symptoms of obsessive-compulsive disorder (OCD) that come on very suddenly. They also may have sudden and severe anxiety, mood swings, irritability, or uncontrollable movements. School performance might suffer, and some kids have sleep problems or a sudden case of bedwetting.

It’s unclear why these symptoms happen. One theory is that an earlier infection may have led to the development of antibodies that — besides attacking the infecting germs — mistakenly targeted an area of the brain that controls behavior.

In the past, some kids with these symptoms were diagnosed as having PANDAS (Pediatric Acute-onset Neuropsychiatric Disorders Associated with Streptococcus). This name was given because it seemed that symptoms were brought on by a streptococcus infection, like strep throat.

Now, however, researchers are finding that symptoms can be triggered by other infections (such as the flu, chickenpox, mycoplasma, and Lyme disease) or may be caused by something else entirely. Because of this, the new name “PANS” was coined to more accurately describe the syndrome (and put the focus on the symptoms, rather than the symptoms and cause). PANDAS, a term still widely in use, is now considered a type of PANS.

PANS isn’t contagious, so kids can’t catch it from a classmate. If a contagious infection (like strep throat) triggered someone’s PANS, that illness can be passed from one person to another. But in general, you don’t have to worry about your child developing PANS. Almost all school-age kids get infections and almost all recover with no complications. Similarly, most kids who have OCD did not get it as a result of PANS.

Scientists are studying PANS to better understand the possible link between infections, OCD, and other symptoms.

Medical Review

  • Last Reviewed: September 14th, 2015
  • Reviewed By: Elana Pearl Ben-Joseph, MD



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