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Cem Demirci, MD

Clinical Director, Pediatric Endocrinology
Medical Director, Diabetes Program
Chase Family Chair in Juvenile Diabetes

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Practice Name Connecticut Children's Specialty Group

Meet Cem Demirci, MD


MD, University of Istanbul, Cerrahpasa School of Medicine, 1991
Pediatrics, Michigan State University, 1994-1997
Pediatric Endocrinology and Diabetes, Children’s Hospital of Pittsburgh, 2006-2009

Board Certifications

  • Pediatric Endocrinology
  • Faculty Appointment

    Assistant Professor of Pediatrics, University of Connecticut School of Medicine

    Clinical Expertise

    Dr. Demirci specializes in Type 1 Diabetes Mellitus (T1DM) care and management. Until there is a cure, he adamantly works to improve the management and care delivery to patients with T1DM. In addition to T1DM, he specializes in monogenic etiologies of Diabetes Mellitus (MODY DM and others) and Cystic Fibrosis related Diabetes (CFRD).

    Selected Publications

    • Disruption of hepatocyte growth factor/c-Met signaling enhances pancreatic beta-cell death and accelerates the onset of diabetes. Mellado-Gil J, Rosa TC, Demirci C, Gonzalez-Pertusa JA, Velazquez-Garcia S, Ernst S, Valle S, Vasavada RC, Stewart AF, Alonso LC, Garcia-Ocaña A. Diabetes. 2011 Feb;60(2):525-36. Epub 2010 Oct 27.

    • Activation of protein kinase C-ζ in pancreatic β-cells in vivo improves glucose tolerance and induces β-cell expansion via mTOR activation.Velazquez-Garcia S, Valle S, Rosa TC, Takane KK, Demirci C, Alvarez-Perez JC, Mellado-Gil JM, Ernst S, Scott DK, Vasavada RC, Alonso LC, Garcia-Ocaña A. Diabetes. 2011 Oct;60(10):2546-59. Epub 2011 Sep 12.

    • Mechanisms in the adaptation of maternal β-cells during pregnancy. Ernst S, Demirci C, Valle S, Velazquez-Garcia S, Garcia-Ocaña A. Diabetes Manag (Lond). 2011 Mar 1;1(2):239-248.

    • Loss of HGF/c-Met signaling in pancreatic β-cells leads to incomplete maternal β-cell adaptation and gestational diabetes mellitus. Demirci C, Ernst S, Alvarez-Perez JC, Rosa T, Valle S, Shridhar V, Casinelli GP, Alonso LC, Vasavada RC, Garcia-Ocaña A. Diabetes. 2012 May;61(5):1143-52. Epub 2012 Mar 16.

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