Ian C. Michelow, MD, FCPaed

Education

Education
MBBCh, University of the Witwatersrand, Johannesburg, South Africa, 1990

Residency
Pediatrics, University of the Witwatersrand, 1994-1997
Pediatrics, Massachusetts General Hospital, 2001-2003 (Chief Resident 2002-2003)

Fellowship
Pediatric Infectious Diseases, University of Texas Southwestern Medical Center, 1998-2001

Board Certifications

Faculty Appointment

Associate Professor, Department of Pediatrics, University of Connecticut School of Medicine

Clinical Expertise

Dr. Michelow’s experience and interests span clinical, basic science and translational research topics with an emphasis on mechanisms of infection across microbial kingdoms, host-pathogen interactions and immune-mediated interventions. His research activities have included the study of malaria pathogenesis and vaccines, Ebola virus disease, clinical epidemiology and biomarkers of bacterial and viral infections in children including COVID-19, congenital syphilis, and pediatric osteoarticular infections, among others. He has also contributed to medical education by mentoring students on emerging infectious diseases research projects under an NIH-sponsored grant and developing new models for clinical teaching.

Dr. Michelow collaborates with colleagues locally, nationally, and internationally. His research has been supported by various charitable foundations, as well as several NIH grants including NIAID K08/U19/R25, NIGMS COBRE, and Fogarty U54. He has a patent for a novel PfEMMA-1 malaria vaccine candidate pending.

Dr. Michelow is Associate Editor of Pneumonia, serves on the editorial board of the Pediatric Infectious Diseases Journal, represents the Pediatric Infectious Diseases Society of America (PIDS) at the World Society for Pediatric Infectious Diseases (WSPID) Education Committee, is a founding leader of WSPID’s International Journal Club, and serves as the Chair-elect of the PIDS International Affairs Committee.

Selected Publications

• IC Michelow, S Park, SW Tsai, B Rayta, S Nelson, CFA Pasaje, A Early, AP Frosch, G Ayodo, DK Raj, CE Nixon, CP Nixon, S Pond-Tor, JF Friedman, M Fried, PE Duffy, KG Le Roch, JD Kurtis, JC Niles. A Newly Characterized Malaria Antigen on Erythrocyte and Merozoite Surfaces Induces Parasite Inhibitory Antibodies. J Exp Med 2021;218(9):e20200170 doi: 10.1084/jem.20200170

• Benjamin Gallo Marin, Ghazal Aghagoli, Katya Lavine, Lanbo Yang, Emily J. Siff, Silvia S. Chiang, Thais P. Salazar-Mather, Luba Dumenco, Michael C Savaria, Su N. Aung, Timothy Flanigan, Ian C. Michelow. Predictors of COVID-19 Severity: A Literature Review. Rev Med Virol 2021;21(1):1-10 doi: 10.1002/rmv.

• Z Alhinai, M Elahi, S Park, B Foo, B Lee, K Chapin, M Koster, PJ Sánchez, IC Michelow. Prediction of adverse outcomes in pediatric acute hematogenous osteomyelitis. Clin Infect Dis 2020;71(9):e454-e464 doi: 10.1093/cid/ciaa211

• Ian C. Michelow*, Michael A. Smit*, Justin Glavis-Bloom, MD, Vanessa Wolfman, Adam C. Levine. Characteristics and Outcomes of Pediatric Patients with Ebola Virus Disease Admitted to Treatment Units in Liberia and Sierra Leone: A Retrospective Cohort Study. Clin Infect Dis 2017;64(3):243-9 doi.org/10.1093/cid/ciw725 (* these authors contributed equally)

• Michelow IC, Wendel GD, Norgard M, Zeray F, Leos NK, Alsaadi R, and Sánchez PJ. Central nervous system invasion by Treponema pallidum in congenital syphilis. N Engl J Med 2002; 346:1792-8. doi: 10.1056/NEJMoa012684

• Ian C. Michelow, Kurt Olsen, Juanita Lozano, Nancy K. Rollins, Lynn B. Duffy, Thedi Ziegler, Jaana Kauppila, Maija Leinonen, George H. McCracken, Jr. Epidemiology and outcome of community-acquired pneumonia in hospitalized children. Pediatrics 2004;113:701-7 doi: 10.1542/peds.113.4.701