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Juan C. Salazar, MD, MPH, FAAP


Executive Vice President of Academic Affairs

Practice Name Connecticut Children's Specialty Group

Education: MD, Pontificia Universidad Javeriana, 1986
MPH, University of Minnesota Medical School, 1995
Residency: Pediatrics, University of Connecticut, Pediatrics, 1988-1992
Fellowship: Pediatric Infectious Diseases, University of Minnesota, 1992-1995

Board Certifications
  • Pediatrics
  • Pediatric Infectious Diseases
  • Faculty Appointment

    Chair, Department of Pediatrics and Professor of Pediatrics, University of Connecticut School of Medicine

    Clinical Expertise

    Dr. Salazar is Physician-in-Chief, Executive Vice President of Academic Affairs at the Medical Center. He is also the Director of the Pediatric and Youth HIV program at Connecticut Children’s and serves as Professor and Chair of the Department of Pediatrics at the UConn School of Medicine.

    Dr. Salazar has received several NIH and private Foundation grants to study Pediatric HIV, congenital syphilis and Lyme disease. Dr. Salazar and his colleagues at the Spirochetal Research laboratories at the University of Connecticut Health Center are actively studying the immune response of children and adults who become infected with the Lyme disease bacterium. He also collaborates with translational and clinical researchers in Southern China and in Cali, Colombia.

    Selected Publications
    • Cruz AR, Ramirez LG, Zuluaga AV, Pillay A, Abreu C, Valencia CA, La Vake C, Cervantes JL, Dunham-Ems S, Cartun R, Mavilio D, Radolf JD and Salazar JC*.  Immune Evasion and Recognition of the Syphilis Spirochete in Blood and Skin of Secondary Syphilis Patients: Two Immunologically Distinct Compartments, PLoS Negl Trop Dis 6(7): e1717, 2012.

    • Roehm CE, Salazar JC, Hagstrom and Valdez TA. Phoma and Acremonium invasive fungal rhinosinusitis in congenital acute lymphocytic leukemia and literature review.  Int J Pediatr Otorhinolaryngol.  Jul 18. [Epub ahead of print], 2012.

    • Anand A, Luthra A, Dunham-Ems S, Caimano M, Karanian C, LeDoyt M, Cruz AR, Salazar JC, and Radolf JD.  TprC/D (Tp0117/131), a trimeric, pore-forming rare outer membrane protein of Treponema pallidum, has a bipartite domain structure”.  Journal of Bacteriology, 194(9): 2331-2333, 2012.

    • Hawley KL, Olson CM, Jr., Iglesias-Pedraz JM, Navasa N, Cervantes JL, Caimano MJ, Izadi H, Ingalls RR, Pal U, Salazar JC, Radolf JD, Anguita J. CD14 Cooperates with Complement Receptor 3 to Mediate MyD88-Independent Phagocytosis of Borrelia burgdorferi. Proc Natl Acad Sci USA. 109(4):1228-32, 2012.

    • Desrosiers DC, Anand A, Luthra A, Dunham-Ems SM, Ledoyt M, Cummings MA, Eshghi A, Cameron CE, Cruz AR, Salazar JC, Caimano MJ, Radolf JD.  TP0326, a Treponema pallidum β-Barrel Assembly Machinery A (BamA) Ortholog and Rare Outer Membrane Protein.  Mol Microbiol. 80:1496-1515, 2011.

    • Stojanov S, Lapidus S, Chitkara P, Feder H, Salazar JC, Fleisher TA, Brown MR, Edwards KM, Ward MM, Colbert RA, Sun HW, Wood GM, Barham BK, Jones A, Aksentijevich I, Goldbach-Mansky R, Athreya B, Barron KS, Kastner DL.  PFAPA syndrome is a disorder of innate immune regulation and Th1 activation responsive to IL-1 blockade.  Apr 8. Proc Natl Acad Sci USA, 108: 7148-7153, 2011.

    • Cervantes JL, Dunham-Ems SM, La Vake CJ, Petzke MM, Sahay B, Sellati TJ, Radolf JD, Salazar JC*.  Phagosomal signaling by Borrelia burgdorferi in human monocytes involves Toll-like receptor (TLR) 2 and TLR8 cooperativity and TLR8-mediated induction of IFN-β. Proc Natl Acad Sci. 108(9):3683-8, 2011.

    • Courter JD, Teevan CJ, Li MH, Girotto JE and Salazar JC*.  Role of tipranavir in treatment of patients with multidrug-resistant HIV.  Ther Clini Risk Manag.  6  431-441, 2010.

    • Cox DL, Luthra A, Dunham-Ems S, Desrosiers DC, Salazar JC, Caimano MJ, Radolf JD. Surface immunolabeling and consensus computational framework to identify candidate rare outer membrane proteins of Treponema pallidum. Infect Immun. 78(12):5178-94, 2010.

    • Desrosiers DC, Bearden SW, Mier I Jr, Abney J, Paulley JT, Fetherston JD, Salazar JC, Radolf JD, Perry RD. Znu is the predominant zinc importer in Yersinia pestis during in vitro growth but is not essential for virulence. Infect Immun. 78(12):5163-5177, 2010.

    • Deville JG, Goldfarb J, Kaplan SL, Equils O, Huang DB, Ang JY, Salazar JC *. The use of linezolid in the treatment of paediatric patients with infections caused by enterococci including strains resistant to vancomycin. J Antimicrob Chemother. 65(10):2267-70, 2010.

    • Cruz AR, Pillay A, Zuluaga AV, Ramirez LG, Duque JE, Aristizabal GE, Fiel-Gan MD,Jaramillo R, Trujillo R, Valencia C, Jagodzinski L, Cox DL, Radolf JD, Salazar JC*.  Secondary syphilis in Cali, Colombia:  New concepts in disease pathogenesis.  PLoS Negl Trop Dis. May 18;4(5):e690, 2010.

    • Courter JD; Girotto JE, Lobato MN, Orcutt D; Burke M, Feder HM; Krause PJ, Cohen-Abbo A, Salazar JC*.  Intravenous streptomycin treatment for treatment of Mycobacterium tuberculosis meningitis in an infant. Pharmacotherapy 30(11): 481e-484e, 2010.

    • Feder Jr. HM and Salazar JC.  A clinical review of 105 patients with PFAPA (A periodic fever syndrome).  Acta Pediatrica, 99(2):178-84, 2010.

    • Kanev P, Salazar JC. Unusual CNS infection from a subtorcular dermal sinus.  Acta Paediatr. 99(4):627-9, 2010.

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