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Michael Isakoff, MD

Division Head, Center for Cancer and Blood Disorders
Director, Sarcoma Program
Director, Reid R. Sacco Adolescent and Young Adult Cancer Program
Medical Director, Connecticut Children’s Clinical Trials Unit
Hartford Whalers’ Endowed Chair in Children’s Cancer

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Practice Name Connecticut Children's Specialty Group


BS, University of Michigan, 1994
MD, New York University School of Medicine, 1999
Pediatrics, Yale-New Haven Children’s Hospital, 1999-2002
Pediatric Hematology/Oncology, Boston Children’s Hospital and Dana-Farber Cancer Institute, 2002-2005

Board Certifications

  • Pediatrics
  • Pediatric Hematology/Oncology
  • Faculty Appointment

    Professor of Pediatrics, University of Connecticut School of Medicine

    Clinical Expertise

    Michael Isakoff, MD, is the Division Head of the Center for Cancer and Blood Disorders. Dr. Isakoff’s expertise includes bone sarcoma, soft tissue sarcoma, rare tumors and clinical trial development.

    Selected Publications

    • Reed DR, Metts J, Pressley M, Fridley BL, Hayashi M, Isakoff MS, Loeb DM, Makanji R, Roberts RD, Trucco M, Wagner LM, Alexandrow MG, Gatenby RA, Brown JS. An evolutionary framework for treating pediatric sarcomas. Cancer. 2020 Jun 1;126(11)2577-2587. doi: 10.1002/cncr.32777. Epub 2020 Mar 16. PubMed PMID: 32176331.

    • Spraker-Perlman HL, Barkauskas DA, Krailo MD, Meyers PA, Schwartz CL, Doski J, Gorlick R, Janeway KA, Isakoff MS. Factors influencing survival after recurrence in osteosarcoma: A report from the Children’s Oncology Group. Pediatr Blood Cancer. 2019 Jan;66(1):e27444. doi: 10.1002/pbc.27444. Epub 2018 Sep 25. PubMed PMID: 30255612; PMCID: PMC6249072.

    • Isakoff MS, Goldsby R, Villaluna D, Krailo MD, Hingorani P, Collier A, Morris CD, Kolb EA, Doski JJ, Womer RB, Gorlick R, Janeway KA. A phase II study of eribulin in recurrent or refractory osteosarcoma: A report from the Children’s Oncology Group. Pediatr Blood Cancer. 2018 Oct 30:e27524. doi: 10.1002/pbc.27524. [Epub ahead of print] PubMed PMID: 30378256.

    • Reed DR, Hayashi M, Wagner L, Binitie O, Steppan DA, Brohl AS, Shinohara ET, Bridge JA, Loeb DM, Borinstein SC, Isakoff MS. Treatment pathway of bone sarcoma in children, adolescents, and young adults. Cancer. 2017 Jun 15;123(12):2206-2218. doi: 10.1002/cncr.30589. Epub 2017 Mar 21. Review. PubMed PMID: 28323337.

    • Isakoff MS, Bielack SS, Meltzer P, Gorlick R. Osteosarcoma: Current Treatment and a Collaborative Pathway to Success. J Clin Oncol. 2015 Sep 20;33(27):3029-35.doi: 10.1200/JCO.2014.59.4895. Epub 2015 Aug 24. Review. PubMed PMID: 26304877.

    Additional Information

    Member of the Children’s Oncology Group (COG) Voting Body Steering Committee (VBSC)

    Patient Feedback

    The Patient Rating score is an average of all responses to physician related questions on our nationally-recognized Patient Satisfaction Survey . Responses are measured on a scale of 1 to 5, with 5 being the best score. Comments also are gathered from our Patient Satisfaction Survey and displayed in their entirety. Patients are de-identified for confidentiality and patient privacy.


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