PANS (Pediatric Acute-onset Neuropsychiatric Syndrome) and a suggested subset, PANDAS (Pediatric Autoimmune Neuropsychiatric Disorders Associated with Streptococcal Infections), are proposed, but to date unsubstantiated, conditions in which a proposed infectious and autoimmune response results in a sudden onset of neuropsychiatric symptoms and functional impairment in a pre-pubertal child. Acute psychiatric symptoms may occur alone or in conjunction with neurologic signs/symptoms and do not exclude other DSM5 diagnoses manifesting similar psychiatric symptoms.
 

Main Guideline
 

References 

These guidelines are intended solely for the use of healthcare professionals who are licensed to practice medicine. This material is not intended to replace professional medical judgment, prescribing information or consultation with a medical professional. Any health care provider using this material acknowledges full responsibility for the medical care and treatment of patients. All health care providers are solely responsible for confirming the accuracy, timeliness, completeness, appropriateness and helpfulness of this material and making all medical, diagnostic or prescription decisions.

For questions about the guidelines, CLASP [at] Connecticutchildrens.org (email the CLASP team).